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Thermo Scientific™ Tango™ ADRA2A-bla U2OS DA Assay-Kit

The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

Marke:  Thermo Scientific™ K1607

Artikelnummer. 10647574

  • 842.00 € / 1 Stück

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Beschreibung

The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ ADRA2A-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ ADRA2A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product. Division Arrested cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.

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User Guide: Tango ADRA2A‑bla U2OS DA and Dividing Cell‑based Assay Version: 2.0 DateigrößeVersion: 783.3 kB
Tango™ ADRA2A-bla U2OS Cell Line Validation Packet Version: version 1.1 DateigrößeVersion: 46.4 kB
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Thermo Scientific™ Tango™ ADRA2A-bla U2OS DA Assay-Kit > 8 x 106 Cells

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Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.