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Bio-Techne is a global developer, manufacturer, and supplier of high-quality reagents, analytical instruments, and precision diagnostics. Whether you’re at the cutting edge of academic research, translating basic discoveries into therapeutic leads, or at a facility that requires the highest level of diagnostic testing, our award-winning tools and solutions empower scientists and clinicians to achieve reproducible and consistent results. Choosing Bio‑Techne means having confidence that every solution you use will help move you towards better answers.
Paris, France 01-05-2024
Thermo Fisher Scientific, a leading provider of laboratory products and services, is pleased to announce a significant milestone in its commitment to providing cutting-edge solutions to its customers. Effective May 1, 2024, Thermo Fisher will enter into a strategic European distribution agreement with Bio-Techne (NASDAQ: TECH), a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities.
This partnership marks an important collaboration between two industry leaders in the fields of scientific research, diagnostics, and biotechnology. Under this agreement, Thermo Fisher, through the Fisher Scientific channel, Europe, will distribute Bio-Techne's extensive portfolio of innovative products, including antibodies, proteins, immunoassay kits, reagents and enzymes to laboratories and research institutions across Europe.
"We are thrilled to forge this partnership with Bio-Techne, a company renowned for its pioneering advancements in the life sciences industry," said Claire Wallace, President, Fisher Scientific channel, Europe. "By adding Bio-Techne's high-quality products to our comprehensive portfolio, we aim to further empower scientists and researchers with the tools they need to drive breakthrough discoveries and advancements in healthcare."
Bio-Techne's state-of-the-art products are designed to accelerate research and improve outcomes in areas including cell and gene therapy, immunology, neuroscience, and more. With this collaboration, Thermo Fisher reinforces its commitment to providing customers with access to the latest technologies and expertise, ultimately advancing scientific knowledge and improving human health.
"We are excited to partner with Thermo Fisher to expand the reach of our products and services throughout Europe," said Kim Kelderman, Bio-Techne’s President and Chief Executive Officer. "By leveraging the Fisher Scientific Channel's extensive European distribution network and industry expertise, we aim to enhance support for researchers and accelerate scientific discoveries that address some of the most pressing challenges in healthcare today."
This distribution agreement underscores Thermo Fisher's dedication to fostering innovation and collaboration within the scientific community. Through strategic partnerships with leading companies like Bio-Techne, Thermo Fisher continues to strengthen its position as a trusted partner for researchers and laboratories across Europe.
Bio-Techne Corporation (NASDAQ: TECH) is a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities. Bio-Techne products assist scientific investigations into biological processes and the nature and progress of specific diseases. They aid in drug discovery efforts and provide the means for accurate clinical tests and diagnoses. With thousands of products in its portfolio, Bio-Techne generated over $1.1 billion in net sales in fiscal year 2023 and has approximately 3,100 employees worldwide.
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Purity or Quality Grade | >95% by SDS-PAGE and HPLC |
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Molecular Weight (g/mol) | 26 kDa |
Gene Symbol | HMGB1 |
Endotoxin Concentration | Less than 1 EU/ug of HMGB1/HMG-1 as determined by LAL method. |
Storage Requirements | Store at -20°C to -70°C as supplied. After reconstitution, store at 2°C to 8°C for 1 month and at -20°C to -70°C for long term storage. Avoid repeated freeze-thaw cycles. |
Concentration | LYOPH |
For Use With (Application) | PAGE |
Protein | HMGB1/HMG-1 |
Accession Number | P09429, P09429, P09429 |
Gene Alias | Amphoterin, high mobility group box 1, High mobility group protein 1, high mobility group protein B1, high-mobility group (nonhistone chromosomal) protein 1, high-mobility group box 1, HMG-1, HMG1DKFZp686A04236, HMG3, SBP-1, Sulfoglucuronyl carbohydrate binding protein |
Gene ID (Entrez) | 3146 |
Formulation | Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4. |
Research Category | Cellular Markers, Chromatin Research, Neuroscience |
Reconstitution | Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20°C. |
Rabbit Polyclonal Antibody has been used in 241 publication
Human Monoclonal Antibody
Content And Storage | Store at -20°C in powder form. Store at -80°C once reconstituted. |
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Target Species | Human |
Host Species | Human |
Conjugate | Unconjugated |
Applications | Flow Cytometry,ELISA,Functional Assay |
Form | Purified |
Isotype | IgG4 |
Gene Accession No. | Q96F85 |
Research Discipline | Cancer, GPCR, Neuroscience, Neurotransmission, Vision |
Antigen | Cannabinoid R1/CB1/CNR1 |
Regulatory Status | RUO |
Purification Method | Protein A purified |
Gene Alias | CANN6CB1R, cannabinoid receptor 1 (brain), CB1A, CB1K5, CB-RCB1cannabinoid receptor 1, central cannabinoid receptor, CNR |
Gene ID (Entrez) | 1268 |
Formulation | Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2) |
Immunogen | CB1/ CNR1 |
Classification | Monoclonal |
Reconstitution | Reconstitute with sterile, distilled water to a final concentration of 1 mg/mL. Gently shake to solubilize completely. Do not vortex. |
Primary or Secondary | Primary |
Clone | nimacimab |
Human Monoclonal Antibody
Content And Storage | Store at -20°C in powder form. Store at -80°C once reconstituted. |
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Target Species | Human |
Host Species | Human |
Conjugate | Unconjugated |
Applications | Flow Cytometry,ELISA,Functional Assay |
Form | Purified |
Isotype | IgG2 |
Research Discipline | GPCR, Growth and Development, Neuronal Cell Markers, Signal Transduction, Wnt Signaling Pathway |
Antigen | Frizzled-9 |
Regulatory Status | RUO |
Purification Method | Protein A purified |
Gene Alias | CD349, CD349 antigen, frizzled (Drosophila) homolog 9, frizzled homolog 9 (Drosophila), frizzled-9, fz-9, FZD3fzE6, FzE6, hFz9 |
Gene ID (Entrez) | 8326 |
Formulation | Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2) |
Immunogen | FZD |
Classification | Monoclonal |
Reconstitution | Reconstitute with sterile, distilled water to a final concentration of 1 mg/mL. Gently shake to solubilize completely. Do not vortex. |
Primary or Secondary | Primary |
Clone | vantictumab |
Rabbit Polyclonal Antibody has been used in 48 publications
Content And Storage | Store at -20C. Avoid freeze-thaw cycles. |
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Target Species | Human,Mouse,Rat,Gerbil |
Host Species | Rabbit |
Conjugate | Unconjugated |
Applications | Western Blot,Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunoprecipitation,Immunohistochemistry (Paraffin),Immunohistochemistry (Frozen),Immunoblot |
Form | Antisera |
Isotype | IgG |
Research Discipline | Apoptosis, Cancer, Caspases, Phospho Specific |
Antigen | Caspase-3 |
Gene Symbols | CASP3 |
Regulatory Status | RUO |
Purification Method | Unpurified |
Dilution | Western Blot 1:1000-1:2000, Flow Cytometry reported in scientific literature (PMID 28287161), Immunohistochemistry, Immunocytochemistry/Immunofluorescence reported in scientific literature (PMID 29963272), Immunoprecipitation 1:50-1:200, Immunohistochemistry-Paraffin 1:1000-1:5000, Immunohistochemistry-Frozen reported in scientific literature (PMID 29864441), Immunoblotting reported in scientific literature (PMID 27912032), Flow (Intracellular) reported in scientific literature (PMID 24804954) |
Molecular Weight of Antigen | 31.7 kDa |
Gene Alias | Apopain, apoptosis-related cysteine protease, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama |
Gene ID (Entrez) | 836 |
Formulation | Neat whole antisera with 0.05% Sodium Azide |
Immunogen | This Caspase-3 Antibody - (active/cleaved) was developed against catalytically active human caspase-3 protein. |
Classification | Polyclonal |
Primary or Secondary | Primary |
Test Specificity | Preferentially detects active caspase-3 (large subunit: ∼14-21 kDa, and small subunit: ∼10 kDa). However, it may also detect pro-caspase-3 (∼32 kDa) in some cell or tissue systems. Nuclear immunostaining of caspase-3 is considered be an indication of active/cleaved caspase-3. |
Rabbit Polyclonal Antibody has been used in 4 publications
Antigen | Factor VIII |
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Gene Symbols | F8 |
Regulatory Status | RUO |
Purification Method | Affinity Purified |
Target Species | Mouse,Rat |
Host Species | Rabbit |
Applications | Western Blot,Immunofluorescence,Immunohistochemistry (Paraffin) |
Immunogen | A synthetic peptide made to a C-terminal portion of human Factor VIII (between amino acids 2100-2250) [UniProt P00451] |
Rat Monoclonal Antibody has been used in 4 publications
Gene Symbols | CD44 |
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Content And Storage | Store at -20C. Avoid freeze-thaw cycles. |
Purification Method | Protein G purified |
Dilution | Western Blot 1:1 - 1:100, Flow Cytometry 1:10 - 1:1000, ELISA 1:100 - 1:2000, Immunohistochemistry 1:10 - 1:2000, Immunocytochemistry/Immunofluorescence 1:10 - 1:200, Immunoprecipitation 1:10 - 1:50, CyTOF-ready, Neutralization |
Classification | Monoclonal |
Mouse Monoclonal Antibody has been used in 89 publications
Content And Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
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Target Species | Human,Mouse,Rat,Pig,Avian,Bovine,Canine,Chicken,Chinese Hamster,Drosophila,Fungi,Guinea Pig,Goat,Hamster,Parasite,Monkey,Primate,Rabbit,Xenopus species,Yeast |
Host Species | Mouse |
Conjugate | Unconjugated |
Applications | Western Blot,Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunoprecipitation,Immunohistochemistry (Paraffin),Immunohistochemistry (Frozen),Immunomicroscopy,CyTOF |
Form | Purified |
Isotype | IgG1 κ |
Research Discipline | Cell Biology, Cell Cycle and Replication, Cytoskeleton Markers, Loading Controls, Neuroscience |
Concentration | 1.0 mg/mL |
Antigen | alpha Tubulin |
Gene Symbols | TUBA1A |
Regulatory Status | RUO |
Purification Method | Protein G purified |
Dilution | Western Blot 1:5000, Simple Western 1:50, Flow Cytometry 1 ug per million cells, Immunohistochemistry 1:100-1:500, Immunocytochemistry/Immunofluorescence 1:50000-1:100000, Immunoprecipitation 1:50-1:100, Immunohistochemistry-Paraffin 1:100-1:500, Immunohistochemistry-Frozen 1:100-1:500, Immunomicroscopy, Flow (Intracellular), CyTOF-ready |
Molecular Weight of Antigen | 50 kDa |
Gene Alias | alpha tubulin loading control, alpha tubulin monoclonal, Alpha-tubulin 3, B-ALPHA-1, DM1A, DM1A anti-tubulin, dm1a monoclonal, DM1a tubulin, FLJ25113, hum-a-tub1, hum-a-tub2, LIS3, TUBA1 monoclonal, TUBA3, tubulin alpha-1A chain, Tubulin alpha-3 chain, Tubulin B-alpha-1, tubulin monoclonal, tubulin, alpha 1a, tubulin, alpha 3, tubulin, alpha, brain-specific |
Gene ID (Entrez) | 7846 |
Immunogen | This alpha Tubulin Antibody (DM1A) was developed against native chicken brain microtubules. |
Classification | Monoclonal |
Primary or Secondary | Primary |
Test Specificity | This alpha Tubulin Antibody (DM1A) does not cross-react with beta Tubulin. |
Clone | DM1A |
Gene Symbols | CA9 |
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Dilution | Western Blot 1 - 3 ug/ml, Simple Western 1:50, Flow Cytometry 1:1000, ELISA reported in scientific literature (PMID 19963243), Immunohistochemistry 1:200 - 1:500, Immunocytochemistry/Immunofluorescence 2 - 5 ug/ml, Immunoprecipitation 1:10 - 1:500. Use reported in multiple pieces of scientific literature, Immunohistochemistry-Paraffin 1:200 - 1:500, Immunohistochemistry-Frozen 1:200 - 1:500, Immunoblotting, Gel Super Shift Assays, Proximity Ligation Assay, Microarray reported in scientific literature (PMID 31955345), Chromatin Immunoprecipitation (ChIP) 1:10-1:500, Dual RNAscope ISH-IHC 1:1000 |
Molecular Weight of Antigen | 55 kDa |
Gene Alias | CA-IX, CAIXcarbonic anhydrase 9, Carbonate dehydratase IX, carbonic anhydrase IXpMW1, carbonic dehydratase, EC 4.2.1.1, G250, Membrane antigen MN, MNRCC-associated antigen G250, P54/58N, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250 |
Content And Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
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Target Species | Human |
Host Species | Rabbit |
Conjugate | Unconjugated |
Applications | Immunohistochemistry,Immunohistochemistry (Paraffin) |
Isotype | IgG |
Antigen | KRT78 |
Gene Symbols | KRT78 |
Regulatory Status | RUO |
Purification Method | Affinity Purified |
Dilution | Immunohistochemistry, Immunohistochemistry-Paraffin 1:200 - 1:500 |
Gene Alias | CK-78, cytokeratin-78, Kb40, keratin 5b, keratin 78, keratin-78, type II cytoskeletal 78 |
Gene ID (Entrez) | 196374 |
Formulation | PBS (pH 7.2) and 40% Glycerol with 0.02% Sodium Azide |
Immunogen | This antibody was developed against Recombinant Protein corresponding to amino acids:VGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSGSS |
Classification | Polyclonal |
Primary or Secondary | Primary |
Test Specificity | Specificity of antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins. |
Content And Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
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Target Species | Human |
Host Species | Rabbit |
Conjugate | Unconjugated |
Applications | Immunohistochemistry (Paraffin) |
Form | Purified |
Isotype | IgG |
Antigen | SCLY |
Regulatory Status | RUO |
Purification Method | Antigen and protein A Affinity-purified |
Dilution | Immunohistochemistry-Paraffin 1:50-1:200 |
Gene Alias | EC 4.4.1.16, SCLhSCL, selenocysteine lyase |
Gene ID (Entrez) | 51540 |
Formulation | PBS (pH 7.0) |
Immunogen | Produced in rabbits immunized with E. coli-derived Human SCLY fragment. |
Classification | Polyclonal |
Primary or Secondary | Primary |
Mouse Monoclonal Antibody