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TC-S 7005, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.
Spezifikation
Spezifikation
| Chemischer Name oder Material | TC-S 7005 |
| CAS | 1082739-92-1 |
| Farbe | Cream |
| Summenformel | C21H17N3O3 |
| Menge | 10 mg |
| Synonym | 2-amino-isoxazolopyridine, 9, 3-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl-isoxazolo 5,4-c pyridin-5-amine, 3-2h-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl pyrido 4,3-d 1,2 oxazol-5-amine |
| InChI-Schlüssel | DAAGOCSHXCDWDY-ZDUSSCGKSA-N |
| SMILES | CC(C1=CC=CC=C1)NC2=NC=C3C(=C2)C(=NO3)C4=CC5=C(C=C4)OCO5 |
| IUPAC-Name | 3-(1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-[1,2]oxazolo[5,4-c]pyridin-5-amine |
| Molekulargewicht (g/mol) | 359.385 |
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