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TC-S 7005, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.
Spezifikation
Chemischer Name oder Material | TC-S 7005 |
CAS | 1082739-92-1 |
Farbe | Cream |
Summenformel | C21H17N3O3 |
Menge | 10 mg |
Synonym | 2-amino-isoxazolopyridine, 9, 3-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl-isoxazolo 5,4-c pyridin-5-amine, 3-2h-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl pyrido 4,3-d 1,2 oxazol-5-amine |
InChI-Schlüssel | DAAGOCSHXCDWDY-ZDUSSCGKSA-N |
SMILES | CC(C1=CC=CC=C1)NC2=NC=C3C(=C2)C(=NO3)C4=CC5=C(C=C4)OCO5 |
IUPAC-Name | 3-(1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-[1,2]oxazolo[5,4-c]pyridin-5-amine |
Molekulargewicht (g/mol) | 359.385 |
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