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NeutraKine IL-17A Mouse anti-Human, Unconjugated, Clone: 1F3E3, Proteintech
Mouse Monoclonal Antibody
149.00 € - 319.00 €
Spezifikation
Antigen | NeutraKine IL-17A |
---|---|
Klon | 1F3E3 |
Anwendungen | Neutralization, ELISA |
Klassifikation | Monoclonal |
Konjugat | Unconjugated |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
17204656
|
Proteintech
69021-1-IG-25UG |
25 μg |
149.00 €
25 Mikrogramm |
Verfügbar ab: 30-07-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
17294646
|
Proteintech
69021-1-IG-100UG |
100 μg |
319.00 €
100 Mikrogramm |
Verfügbar ab: 30-07-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased. This antibody is used to Block/Neutralize IL-17A protein.
Spezifikation
NeutraKine IL-17A | |
Neutralization, ELISA | |
Unconjugated | |
Mouse | |
IgG1 |
1F3E3 | |
Monoclonal | |
Liquid | |
3605 | |
Primary |