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NeutraKine IL-17A Mouse anti-Human, Unconjugated, Clone: 1F3E3, Proteintech

Mouse Monoclonal Antibody

Marke:  Proteintech 69021-1-IG-25UG

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Artikelnummer. 17204656

  • 149.00 € / 25 Mikrogramm

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Beschreibung

Beschreibung

IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased. This antibody is used to Block/Neutralize IL-17A protein.

Spezifikation

Spezifikation

NeutraKine IL-17A
Monoclonal
Unconjugated
25 μg
3605
Liquid
Neutralization, ELISA
1F3E3
Mouse
Primary
Human, Mouse, Rat
IgG1
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
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