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CD3 Mouse, anti-Human, FITC, Clone: SK7, STEMCELL Technologies
Mouse Monoclonal Antibody
144.45 € - 322.65 €
Spezifikation
| Antigen | CD3 |
|---|---|
| Klon | SK7 |
| Anwendungen | Flow Cytometry |
| Klassifikation | Monoclonal |
| Konjugat | FITC |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
17139161
|
Stemcell Technologies
60127FI.1 |
25 Tests |
144.45 €
25 Tests |
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|
17129161
|
Stemcell Technologies
60127FI |
100 Tests |
322.65 €
100 Tests |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
- The SK7 antibody reacts with the ∼20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ∼95% of mature T cells and NKT cells, and variably on thymocytes
- A majority of T cell neoplasms also express CD3
- The CD3 complex, which is assembled from combinations of CD3γ, δ, ε, η and ζ subunits, associates non-covalently with the TCR and is involved in transducing antigen recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR
- Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related type 1 transmembrane proteins and members of the immunoglobulin superfamily
- Mutations in the CD3 subunits have been associated with various immunodeficiency disorders, including severe combined immunodeficiency (SCID)
Spezifikation
| CD3 | |
| Flow Cytometry | |
| FITC | |
| Chimpanzee, Human | |
| Primary |
| SK7 | |
| Monoclonal | |
| Mouse | |
| IgG1 κ |
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