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Thiamet G, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
Potent, selective inhibitor of O-GlcNAcase (Ki = 21 nM for human O-GlcNAcase). Decreases the phosphorylation of tau protein in vivo. Promotes autophagy independently of mTOR pathway and reduces toxic protein species in mouse tauopathy model. Orally bioavailable and blood brain barrier permeable.
Spezifikation
Spezifikation
| Chemischer Name oder Material | Thiamet G |
| CAS | 1009816-48-1 |
| Summenformel | C9H16N2O4S |
| Menge | 10 mg |
| Synonym | thiamet g |
| InChI-Schlüssel | PPAIMZHKIXDJRN-LQOSVEJXSA-N |
| SMILES | CCNC1=NC2C(C(C(OC2S1)CO)O)O |
| IUPAC-Name | (3aS,5R,6R,7S,7aS)-2-(ethylamino)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol |
| Molekulargewicht (g/mol) | 248.297 |
| PubChem CID | 122172999 |
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