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TGF-beta Antibody (1D11.16.8) - Azide and BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody
Marke: Novus Biologicals NBP2-47736-0.1MG
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Beschreibung
TGF-beta Monoclonal specifically detects TGF-beta in Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey samples. It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Functional, Sandwich ELISA, Neutralization, ELISA Capture (Matched Antibody Pair), Inhibition Activity.
Spezifikation
| TGF-beta | |
| Monoclonal | |
| 1.0 mg/mL | |
| Immunocytochemistry/Immunofluorescence 8-25 ug/ml, Immunohistochemistry-Paraffin : 0.5 - 1.0ug/ml, Functional, Sandwich ELISA, Neutralization, ELISA Capture (Matched Antibody Pair), Inhibition Activity | |
| TGFB1 | |
| Bovine TGF-beta2 protein | |
| Protein A or G purified | |
| RUO | |
| 7040 | |
| Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey | |
| Purified |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Functional Assay, ELISA, Neutralization | |
| 1D11.16.8 | |
| Unconjugated | |
| PBS with No Preservative | |
| Mouse | |
| 13 kDa | |
| 0.1 mg | |
| Primary | |
| This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. | |
| Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
| IgG1 κ |
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