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TC ASK 10, Tocris Bioscience™
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Menge:
10 mg
50 mg
Beschreibung
Potent ASK1 inhibitor (IC50 = 14 nM); displays selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 values are > 10 μM). Blocks downstream JNK1/p38 phosphorylation in cells. Orally bioavailable.
Spezifikation
Chemischer Name oder Material | TC ASK 10 |
Menge | 10 mg |
Formelmasse | 432.35 |
Reinheit (%) | >98% |
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