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  5. Tocris Bioscience™ SB 271046 hydrochloride

Tocris Bioscience™ SB 271046 hydrochloride
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Product Code. 18074492
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Menge:
10 mg
50 mg
Unit Size:
10 Milligramm
50 Milligramm
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Product Code. 18074492

Brand: Tocris Bioscience™ 3368/10

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Description

Selective, orally active 5-HT6 antagonist

Selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.55, 6.35, 6.27, 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT6, 5-HT1D, 5-HT1A, D3, 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. Increases extracellular glutamate and aspartate in the frontal cortex, and exhibits anticonvulsant activity (EC50 = 0.16 μM).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 209481-20-9
Summenformel C20H23Cl2N3O3S2

Specifications

Chemischer Name oder Material SB 271046 hydrochloride
Menge 10 mg
Formelmasse 488.45
Reinheit >99%
Molekulargewicht 488.442
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