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RO-3, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
Selective homomeric P2X3 and heteromeric P2X2/3 receptor antagonist (pIC50 values are 7.0 and 5.9 respectively) that exhibits no activity at P2X1, P2X2, P2X4, P2X5 and P2X7 receptors (IC50 > 10 μM). Attenuates nociceptive sensitivity in animal models of pain. Orally active and brain penetrant.
Spezifikation
Spezifikation
| Chemischer Name oder Material | RO-3 |
| CAS | 1026582-88-6 |
| Summenformel | C16H22N4O2 |
| Menge | 10 mg |
| Synonym | ro-3, ro3, 5-4,5-dimethoxy-2-methylethyl phenyl methyl-2,4-pyrimidinediamine, d0g8ni, 5-4,5-dimethoxy-2-propan-2-yl phenyl methyl pyrimidine-2,4-diamine |
| InChI-Schlüssel | PYNPWUIBJMVRIG-UHFFFAOYSA-N |
| SMILES | CC(C)C1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC |
| IUPAC-Name | 5-[(4,5-dimethoxy-2-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine |
| Molekulargewicht (g/mol) | 302.378 |
| PubChem CID | 11289644 |
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