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Retinoic acid, Tocris Bioscience™
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Menge:
50 mg
Beschreibung
Retinoic acid is an endogenous agonist for retinoic acid receptors (IC50 = 14 nM for RARα, RARβ and RARγ receptors). Also promotes differentiation of mouse embryonic stem cells (ESCs) into adipocytes, neurons and glia in vitro. Proposed ligand of RORβ (Kd = 280 nM). Activates autophagy.
For more information about how Retinoic acid may be used, see our protocols: Generation of β cells from hPSCs, Cultivating Cerebral Organoids .
Spezifikation
Spezifikation
| Chemischer Name oder Material | Retinoic acid |
| CAS | 302-79-4 |
| Summenformel | C20H28O2 |
| MDL-Nummer | MFCD00001551 |
| Menge | 50 mg |
| Synonym | retinoic acid, tretinoin, vitamin a acid, all-trans-retinoic acid, trans-retinoic acid, renova, airol, retin-a, vesanoid, atra |
| InChI-Schlüssel | SHGAZHPCJJPHSC-YCNIQYBTSA-N |
| SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O |
| IUPAC-Name | (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid |
| Molekulargewicht (g/mol) | 300.44 |
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