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Thermo Scientific™ (R,R)-Chloramphenicol, 98%
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Menge:
25g
100g
Beschreibung
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
- (R,R)-chloramphenicol is a compound with antibiotic and bacteriostatic activity and is derived from Streptomyces venequelae
- It that can block the translation on the 50S subunit at the peptidyltransferase step. The binding affects the peptidyl transferase activity, preventing the transfer of amino acids to the growing peptide chains and inhibiting peptide bond formation. The resulting inhibition of the bacterial protein synthesis impedes bacterial cell proliferation
Application
- (R,R)-chloramphenicol has been used for several molecular biology approaches, mainly for bacterial selection. It can be used to select transformed cells containing chloramphenicol resistance genes
- This compound can also promote mitochondrial and chloroplast protein synthesis and the ribosomal formation of (p)ppGpp, depressing the rRNA transcription process
- In vitro results demonstrate that (R,R)-chloramphenicol shows activity against several vancomycin-resistant E. faecium strains
Spezifikation
Spezifikation
| Chemischer Name oder Material | Chloramphenicol |
| Menge | 25g |
| Prozentgehaltsbereich | 0.99 |
| Beilstein | 2225532 |
| Merck Index | 14,2077 |
| Löslichkeitsinformationen | Soluble in alcohol,propylene,glycol,acetone and ethyl acetate. Slightly soluble in water. |
| Formelmasse | 323.14 |
| Reinheit (%) | ≥99% |
Sicherheit und Handhabung
Produktidentifikator
- (R,R)-Chloramphenicol
- Gefahr
- Karzinogenität Kategorie 1B
- H350-Kann Krebs erzeugen.
- P201-Vor Gebrauch besondere Anweisungen einholen.
- P308+P313-BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
- MIXTURE LIST-Enthält: Chloramphenicol
RUO – Research Use Only
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