Tocris Bioscience™ (R)-2-Hydroxyglutaric acid disodium salt, Tocris Bioscience™

KDM4A inhibitor; also NF-κB activator

Marke: Tocris Bioscience™ 6124/50

Artikelnummer. 18761348

163.06 € / 50 Milligramm

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Descrizione

(R)-2-Hydroxyglutaric acid disodium salt is an oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF-κB in bone marrow stromal cells and inhibits FTO (mRNA N6-methyladenine demethylase).

Specifica

Chemischer Name oder Material	(R)-2-Hydroxyglutaric acid disodium salt
Synonym	(R)-2-Hydroxypentanedioic acid disodium salt
Löslichkeit	Löslich zu 100 mM in Wasser
Formelmasse	192.08
Farbe	Weiß

CAS	103404-90-6
Menge	50 mg
Summenformel	C₅H₆Na₂O₅
Physikalische Form	Fest
Produkttyp	Bioactive Small Molecule

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Tocris Bioscience™ (R)-2-Hydroxyglutaric acid disodium salt, Tocris Bioscience™

Descrizione

Specifica

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