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Invitrogen™ POLB Recombinant Rabbit Monoclonal Antibody (6M8I5)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA535359
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Beschreibung
Immunogen sequence: MGVCQLPSKN DEKEYPHRRI DIRLIPKDQY YCGVLYFTGS DIFNKNMRAH ALEKGFTINE YTIRPLGVTG VAGEPLPVDS EKDIFDYIQW KYREPKDRSE.
DNA polymerase beta comprises an amino-terminal 8- kDa domain and a carboxy-terminal 31- kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level. DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.
Spezifikation
| POLB | |
| Recombinant Monoclonal | |
| 0.22 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P06746, P06766, Q8K409 | |
| POLB | |
| A synthetic peptide corresponding to a sequence within amino acids 236-335 of human DNA Polymerase beta (P06746). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 6M8I5 | |
| Unconjugated | |
| POLB | |
| A430088C08Rik; DNA pol beta; DNA polymerase beta; DNA polymerase beta subunit; DNA-directed DNA polymerase beta; hypothetical protein LOC614688; LOW QUALITY PROTEIN: DNA polymerase beta; MGC125976; POL B; Pol beta; POLB; polb.S; polymerase (DNA directed), beta; polymerase (DNA directed), beta S homeolog; polymerase (DNA) beta; polymerase B; polymerase-beta; wu:fa97a05; XELAEV_18020165mg; zgc:109924 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 18970, 29240, 5423 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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