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Invitrogen™ Phospho-CDK2 (Thr160) Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA577906
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Beschreibung
Positive Control: 293T, HeLa, HeLa (10 mM Hydroxyurea treatment for 18 hr) Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Pig (100%), Chicken (100%), Sheep (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
Spezifikation
| Phospho-CDK2 (Thr160) | |
| Polyclonal | |
| Unconjugated | |
| CDK2 | |
| A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1017 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 3.35 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P24941 | |
| CDK2 | |
| Carrier-protein conjugated synthetic peptide surrounding phospho Thr160 of human CDK2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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