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NNC 711, Tocris Bioscience™

Artikelnummer. 18084582
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Menge:
10 mg
50 mg
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Beschreibung

Selective GAT-1 inhibitor

Potent and selective inhibitor of GABA uptake by GAT-1 (IC50 values are 0.04, 171, 1700 and 622 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Anticonvulsant following systemic administration in vivo. Also exhibits cognition-enhancing activity.

Chemische Identifikatoren

CAS 145645-62-1
Summenformel C21H23ClN2O3
Molekulargewicht (g/mol) 386.876
InChI-Schlüssel YZYRTEYMUTWJPL-UHFFFAOYSA-N
Synonym no-711 hydrochloride, 1-2-diphenylmethylene amino oxy ethyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-2-diphenylmethylene amino oxy ethyl-3-pyridinecarboxylic acid hydrochloride, 1-2-diphenylmethylene imino oxy ethyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride hydrochloride, 3-pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-2-diphenylmethylene amino oxy ethyl-, monohydrochloride, c21h22n2o3.hcl, no-711 hydrochloride hplc, 1-2-diphenylmethylene imino oxy ethyl-1,2,5,6-tetrahydro-3-pyridine-carboxylic acid hydrochloride, 1-2-diphenylmethylidene amino oxy ethyl-5,6-dihydro-2h-pyridine-3-carboxylic acid hydrochloride, 1-2-benzhydrylideneamino oxyethyl-3,6-dihydro-2h-pyridine-5-carboxylic acid hydrochloride
PubChem CID 123738
IUPAC-Name 1-[2-(benzhydrylideneamino)oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid;hydrochloride
SMILES C1CN(CC(=C1)C(=O)O)CCON=C(C2=CC=CC=C2)C3=CC=CC=C3.Cl

Spezifikation

Chemischer Name oder Material NNC 711
Menge 10 mg
Formelmasse 386.88
Reinheit (%) >99%
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