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NCL 00017509, Tocris Bioscience™
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Menge:
1 mg
Beschreibung
NCL 00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo. In mice bearing pancreatic tumors, NCL 00017509 decreases PD-L1 expression and induces an anticancer immune response.
Spezifikation
Spezifikation
| Chemischer Name oder Material | 3-[(6-Ethynyl-9H-purin-2-yl)amino]benzeneacetamide |
| CAS | 1507367-00-1 |
| Hinweise zur Reinheitsqualität | >97% |
| Summenformel | C15H12N6O |
| Strukturformel | C15H12N6O |
| Menge | 1 mg |
| Synonym | 3-6-ethynyl-9h-purin-2-yl amino benzeneacetamide |
| Löslichkeitsinformationen | Soluble to 100mM in DMSO |
| InChI-Schlüssel | CJQGLUJHMXCLQY-UHFFFAOYSA-N |
| SMILES | C#CC1=C2C(=NC(=N1)NC3=CC=CC(=C3)CC(=O)N)N=CN2 |
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