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Metformin hydrochloride, Tocris Bioscience™

Artikelnummer. 30001457
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Menge:
100 mg
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Activator of LKB1/AMPK; antidiabetic agent

Metformin hydrochloride is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines via inhibition of mitochondrial complex I (MRC-1). Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.

Spezifikation

Chemischer Name oder Material Metformin hydrochloride
CAS 1115-70-4
Summenformel C4H12ClN5
MDL-Nummer MFCD00012582
Menge 100 mg
Synonym metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
InChI-Schlüssel OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES [H+].[Cl-].CN(C)C(=N)N=C(N)N
IUPAC-Name Wasserstoff-1-[(Diaminomethyliden)amino]-N,N-dimethylmethanimidamid-chlorid
Molekulargewicht (g/mol) 165.63
PubChem CID 14219
Formelmasse 165.62
Reinheit (%) >98%
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