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LEI 101 hydrochloride, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
Potent and selective CB2 partial agonist (pEC50 = 8.0). Exhibits >100-fold selectivity for CB2 over CB1 and no significant interaction with hFAAH, MAGL, DAGL or NAPE-PLD. Displays antinociceptive activity in a rat neuropathic pain model and attenuates renal inflammation in a mouse kidney damage model. Orally bioavailable with low brain penetration.
Spezifikation
Spezifikation
| Chemischer Name oder Material | 3-Cyclopropyl-1-[[4-[6-[(1,1-dioxido-4-thiomorpholinyl)methyl]-5-fluoro-2-pyridinyl]phenyl]methyl]-2 |
| CAS | 2250025-91-1 |
| Hinweise zur Reinheitsqualität | >98% |
| Strukturformel | C23H25FN4O4S.HCl |
| Menge | 10 mg |
| Synonym | LEI 101 hydrochloride |
| Löslichkeitsinformationen | Soluble to 100mM in DMSO |
| Formelmasse | 508.99 |
| Physikalische Form | Solid |
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