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  7. IEM 1925 dihydrobromide, Tocris Bioscience™

IEM 1925 dihydrobromide, Tocris Bioscience™

Artikelnummer. 18075452
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Menge:
10 mg
50 mg
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Beschreibung

Voltage- and use-dependent open-channel antagonist of AMPA receptors

IEM 1925 dihydrobromide is a voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking receptors more potently than GluA2-containing receptors (KD for GluA2-containing AMPAR is 210 times higher at -80 mV). More potent than IEM 1460 (Cat. No. 1636) and IEM 1754 due to a slower unblocking rate. Alleviates inflammatory pain in a rat model of peripheral inflammation.

Chemische Identifikatoren

CAS 258282-23-4
Summenformel C17H30Br2N2
Molekulargewicht (g/mol) 422.249
InChI-Schlüssel ZCYUSVRXEKAQSL-UHFFFAOYSA-N
Synonym iem 1925 dihydrobromide, n-1-phenylcyclohexyl-1,5-pentanediamine dihydrobromide
PubChem CID 44561101
IUPAC-Name N'-(1-phenylcyclohexyl)pentane-1,5-diamine;dihydrobromide
SMILES C1CCC(CC1)(C2=CC=CC=C2)NCCCCCN.Br.Br

Spezifikation

Chemischer Name oder Material IEM 1925 dihydrobromide
Menge 10 mg
Formelmasse 422.24
Reinheit (%) 95%
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