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Tocris Bioscience™ I-BET 762
Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.
Marke: Tocris Bioscience™ 6521/25
386.89 EUR gültig bis 2024-12-16
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Beschreibung
I-BET 762 is a potent and high affinity BET bromodomain inhibitor (IC50 = 32.5 - 42.5 nM; Kd = 50.5 - 61.3 nM). Inhibits myeloma cell proliferation. Attenuates transcription of oncogenic MYC and suppresses key inflammatory genes. Exhibits efficacy in a range of oncology and immunoinflammatory models. Displays antiproliferative effect in vitro and in vivo. Orally bioavailable.Spezifikation
| (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide | |
| 25 mg | |
| C22H22ClN5O2 |
| 1260907-17-2 | |
| Bromodomain Inhibitors | |
| 0.98 |