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Diphenyleneiodonium chloride, Tocris Bioscience™

Artikelnummer. 18084912
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Menge:
10 mg
50 mg
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Beschreibung

GPR3 agonist; also inhibits NOS and NADPH oxidases

GPR3 agonist (EC50 = 1 μM); activates adenylate cyclase through GPR3 but not GPR6 or GPR12. Also induces Ca2+ mobilization and β-arrestin receptor internalization. Binds strongly to flavoproteins; inhibits several enzymes, including NO synthase, NADPH oxidases and NADPH cytochrome P450 oxidoreductase. Also inhibits platelet aggregation.

Chemische Identifikatoren

CAS 4673-26-1
Summenformel C12H8ClI
Molekulargewicht (g/mol) 314.55
InChI-Schlüssel FCFZKAVCDNTYID-UHFFFAOYSA-M
Synonym diphenyleneiodonium chloride, dibenziodolium chloride, unii-7m9d81yz2n, dpi, 8? 3-iodatricyclo 7.4.0.0 2 ,? trideca-1 13 ,2,4,6,9,11-hexaen-8-ylium chloride, dibenziodolium, chloride, d0n0gj, c12h8i.cl, dibenzo b,d iodolium chloride, 2,2'-biphenylyleneiodonium chloride
PubChem CID 2733504
ChEBI CHEBI:77967
SMILES C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]

Spezifikation

Chemischer Name oder Material Diphenyleneiodonium chloride
Menge 50 mg
Formelmasse 314.55
Reinheit (%) >99%
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