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Cyclic Pifithrin-α hydrobromide, Tocris Bioscience™

Artikelnummer. 18085402
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Menge:
10 mg
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Beschreibung

p53 inhibitor

Cyclic Pifithrin-α hydrobromide is a cyclic analog of pifithrin-α (Cat. No. 1267), a small molecule inhibitor of p53. Prevents dexamethasone -induced cell death in murine thymocytes (EC50 = 2.01 μM). Sensitizes p53-deficient tumors to radiotherapy and chemotherapy; increases apoptosis in target cells when used in combination with antimicrotubule agents.

Chemische Identifikatoren

CAS 511296-88-1
Summenformel C16H17BrN2S
Molekulargewicht (g/mol) 349.29
MDL-Nummer MFCD02683960
InChI-Schlüssel SGNCOAOESGSEOP-UHFFFAOYSA-N
Synonym pifithrin-beta hydrobromide, cyclic pifithrin-alpha hydrobromide, pifithrin-alpha, cyclic, unii-up003xxt4d, up003xxt4d, 2-4-methylphenyl imidazo 2,1-b-5,6,7,8-tetrahydrobenzothiazole, hbr, 2-4-methylphenyl imidazo 2,1-b-5,6,7,8-tetrahydrobenzothiazole hydrobromide, cyclic pifithrin-, a hydrobromide, pifithrin-beta hydrobromide mi, cyclic-pifithrin-alpha
PubChem CID 11515812
IUPAC-Name 4-(4-methylphenyl)-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶]dodeca-1(8),3,5-triene hydrobromide
SMILES Br.CC1=CC=C(C=C1)C1=CN2C(SC3=C2CCCC3)=N1

Spezifikation

Chemischer Name oder Material Cyclic Pifithrin-α hydrobromide
Menge 10 mg
Formelmasse 349.29
Reinheit (%) >98%
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