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ACROBiosystems Biotinylated Human NKG2A & CD94 Protein, Fc, Avitag™

Artikelnummer. 17106531
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Menge:
200 μg
25 μg
Packungsgröße:
200 Mikrogramm
25 Mikrogramm

Artikelnummer. 17106531

Marke: ACROBiosystems NC4H82F5200ug

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Biotinylated Protein

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 40.4 kDa & 42.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Spezifikation

Zugriffsnummer NP_002250.1 (NKG2A) and N/A
Molekulargewicht 40.4 kDa and 42.3 kDa
Menge 200 μg
Quelle Biotinylated Human NKG2A&CD94;, Fc,Avitag™ (NC4-H82F5) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 and Asp 57-Ile 179 (Accession # P26715-1 (NKG2A) and Q13241-1 (CD94)).
Immunogen Ala 113 - Leu 233 and Asp 57-Ile 179
Lagerungsbedingungen -20°C
Gen-Alias NKG2A and CD94
Gebräuchliche Bezeichnung NKG2A and CD94
Konjugat Precision Avi
Spezies Human
Proteinmarkierung Fc Tag and Avi Tag
Puffer PBS, pH7.4
Endotoxin-Gehalt Less than 1.0 EU / μg by the LAL method.
Expressionssystem HEK293
Form Powder
Protein-Subtyp MABSol™ Biotin Labeled Proteins
Reinheits- oder Qualitätsgrad >95% as determined by SDS-PAGE
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