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TOLLIP Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA520204
338.68 EUR gültig bis 2025-03-29
Benutzen Sie den Promotions-Code "24111" um Ihren Promotions-Preis zu erhalten.
Benachrichtigungen:
Um den Rabatt von 33.33 % zu erhalten, müssen Kunden drei Einheiten desselben Produkts zum Listenpreis in einer einzigen Bestellung kaufen. Es gibt keine Begrenzung für die Anzahl von 3er Sets, die Kunden kaufen können. PCODE: 24111
Beschreibung
A suggested positive control is rat brain tissue lysate. PA5-20204 can be used with blocking peptide PEP-0345.
Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
Spezifikation
| TOLLIP | |
| Polyclonal | |
| Unconjugated | |
| TOLLIP | |
| 4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 361677, 54472, 54473 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| A2RUW1, Q9H0E2, Q9QZ06 | |
| TOLLIP | |
| A 16 amino acid peptide from near the carboxy terminus of human TOLLIP. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Name des Produkts
TOLLIP Polyclonal Antibody, Invitrogen™ > 100 μg; Unconjugated
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