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RET Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA538509
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Beschreibung
RET is a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases which are cell-surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
Spezifikation
Ret | |
Polyclonal | |
Unconjugated | |
RET | |
C-ret, EC 2.7.10.1, Proto-oncogene ret precursor, kinase Ret | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
19713, 24716, 5979 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P07949, P35546, G3V9H8 | |
RET | |
A synthetic non-phosphopeptide derived from human Ret around the phosphorylation site of Tyr905 (D-S-YP-V-K) | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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Name des Produkts
RET Polyclonal Antibody, Invitrogen™ > 100 μg; Unconjugated
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