missing translation for 'onlineSavingsMsg'
Learn More
Learn More
RAD17 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA14131
Dieser Artikel kann nicht zurückgegeben werden.
Rückgaberichtlinie anzeigen
Beschreibung
PA1-4131 detects yeast RAD17. PA1-4131 has been successfully used in Western blot procedures. By Western blot this antibody detects a ∽75 kDa protein representing RAD17 in yeast. The PA1- 4131 immunogen is a synthetic peptide corresponding to residues S(10) T K R S L K K K K I R K I(23) of the 75 kDa S. pombe RAD17.
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
Spezifikation
| RAD17 | |
| Polyclonal | |
| Unconjugated | |
| Rad17 | |
| CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 854550 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P48581 | |
| Rad17 | |
| Synthetic peptide corresponding to residues S(10) T K R S L K K K K I R K I(23) of the 75 kDa S. pombe RAD17. | |
| 100 μg | |
| Primary | |
| Yeast | |
| Antibody | |
| IgG |