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CD206 Mouse anti-Human, PE, Clone: 19.2, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 555954
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Beschreibung
The 19.2 monoclonal antibody specifically binds to CD206 which is also known as the macrophage mannose receptor (MMR) or C-type lectin domain family 13 member D (CLEC13D). CD206 is a type I transmembrane glycoprotein of approximately 162 kDa which binds to glycoconjugates containing mannose, fucose, or N-acetylglucosamine. These carbohydrates are present on the surface of many microorganisms and enable the macrophage to bind to microorganisms through the MMR and internalize them during the process of phagocytosis. CD206 is expressed on human macrophages, endothelial cells, and cultured dendritic cells. It is not detected on resting monocytes. Mannose receptor expression is upregulated on peripheral blood mononuclear cells following 3 day incubation with GM-CSF.
Spezifikation
| CD206 | |
| Monoclonal | |
| PE | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human Placental Macrophage Mannose Receptor | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| 19.2 | |
| Macrophage mannose receptor | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.