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ACET, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
Potent and selective GluK1 (formerly GluR5) containing kainate receptor antagonist (IC50 = 7 nM) that displays selectivity over GluK2 (formerly GluR6) containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.
Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
Spezifikation
Spezifikation
| Chemischer Name oder Material | ACET |
| CAS | 936095-50-0 |
| Summenformel | C20H21N3O6S |
| Menge | 10 mg |
| Synonym | (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2, 4-dione |
| InChI-Schlüssel | OAAMYRWMIRGBQF-UHFFFAOYSA-N |
| SMILES | CC1CN(C(=O)N(C1=O)CC2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)CC(C(=O)O)N |
| IUPAC-Name | 3-[[3-(2-amino-2-carboxyethyl)-5-methyl-2,6-dioxo-1,3-diazinan-1-yl]methyl]-5-phenylthiophene-2-carboxylic acid |
| Molekulargewicht (g/mol) | 431.463 |
| PubChem CID | 118797384 |
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