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Thermo Scientific™ Human ABL1 [Y253F], His Tag Recombinant Protein
Human ABL1 [Y253F], His Tag Recombinant Protein
Marke: Thermo Scientific™ PV3863
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Beschreibung
- The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response
- The Y253F mutant is a Gleevec resistant form of ABL1
Spezifikation
NP_005148.2, Y253F | |
25, 9586 | |
10 μg | |
ABL Kinase Family | |
Human | |
His Tag | |
Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic | |
Dry Ice | |
ABL1 Y253F | |
Baculovirus | |
Full Length, Recombinant, Cytoplasmic | |
Cytoplasmic Tyrosine Kinases |
Kinase Assay | |
125.4 kDa | |
ABL1 Y253F, ABL, c-ABL | |
Full Length (Y253F) | |
Recombinant | |
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% NP-40, 2 mM DTT and 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
|
Tyrosine Kinases | |
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™, Omnia™ Bulk Substrate | |
c-abl oncogene 1, receptor tyrosine kinase | |
Kinases & Inhibitors | |
Liquid | |
Oncology, Signal Transduction |