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8-pCPT-2-O-Me-cAMP-AM, Tocris Bioscience™
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Menge:
100 μg
Beschreibung
Selective Epac activator; cAMP analog. Induces Rap activation and junction tightening in HUVECs; triggers adhesion of Jurkat-Epac1 cells to fibronectin. Stimulates insulin secretion in rat INS-1 cells. More potent, cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645).
This product is a mixture of axial and equatorial isomers. Both isomers give 8CPT-2Me-cAMP after esterase cleavage.
Spezifikation
Spezifikation
| Chemischer Name oder Material | EPAC Activators |
| CAS | 1152197-23-3 |
| Summenformel | C20H21ClN5O8PS |
| Menge | 100 μg |
| Synonym | 8-pcpt-2-o-me-camp-am, 8-cpt-am, 8-4-chlorophenylthio-2'-o-methyladenosine-3',5'-cyclic monophosphate acetoxymethyl ester |
| InChI-Schlüssel | FZMWUFYPEVDWPA-SILPBKOMSA-N |
| SMILES | CC(=O)OCOP1(=O)OCC2C(O1)C(C(O2)N3C4=C(C(=NC=N4)N)N=C3SC5=CC=C(C=C5)Cl)OC |
| IUPAC-Name | [(4aR,6R,7R,7aR)-6-[6-amino-8-(4-chlorophenyl)sulfanylpurin-9-yl]-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-yl]oxymethyl acetate |
| Molekulargewicht (g/mol) | 557.899 |
| PubChem CID | 90488978 |
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