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8-CPT-2Me-cAMP, sodium salt, Tocris Bioscience™
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Menge:
1 mg
Beschreibung
Selective activator of Epac, the cAMP-sensitive guanine nucleotide-exchange factor for Rap1 and Rap2. Activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 > 10 μM). Stimulates Epac-mediated Ca2+-mediated Ca2+ release in pancreatic β-cells in vitro. Cell permeable analog (Cat. No. 4853) also available.
Spezifikation
Spezifikation
| Chemischer Name oder Material | EPAC Activators |
| CAS | 634207-53-7 |
| Summenformel | C17H17ClN5NaO6PS |
| Menge | 1 mg |
| Synonym | 8-cpt-2me-camp, sodium salt |
| InChI-Schlüssel | IORFFVUNBNOFAO-KHXPSBENSA-N |
| SMILES | COC1C2C(COP(=O)(O2)O)OC1N3C4=C(C(=NC=N4)N)N=C3SC5=CC=C(C=C5)Cl.[Na] |
| IUPAC-Name | 9-[(4aR,6R,7R,7aR)-2-hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-chlorophenyl)sulfanylpurin-6-amine;sodium |
| Molekulargewicht (g/mol) | 508.826 |
| PubChem CID | 131856562 |
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