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2-APB, Tocris Bioscience™

Catalog Number 18075342
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Menge:
10 mg
50 mg
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
524-95-8
C14H16BNO
225.10
MFCD00014823
BLZVCIGGICSWIG-UHFFFAOYSA-N
2-aminoethyl diphenylborinate, 2-apb, 2-aminoethoxy diphenylborane, 2-aminoethoxydiphenylborane, 2-aminoethoxydiphenylborate, 2-aminoethoxydiphenyl borate, o-2-aminoethyl diphenylborinic acid, b-2-aminoethoxy diphenylborane, 2-diphenylboryl oxy ethanamine, borinic acid, o-2-aminoethyl diphenyl
1598
2-Aminoethyldiphenylborinat
NCCOB(C1=CC=CC=C1)C1=CC=CC=C1
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
524-95-8
C14H16BNO
225.10
MFCD00014823
BLZVCIGGICSWIG-UHFFFAOYSA-N
2-aminoethyl diphenylborinate, 2-apb, 2-aminoethoxy diphenylborane, 2-aminoethoxydiphenylborane, 2-aminoethoxydiphenylborate, 2-aminoethoxydiphenyl borate, o-2-aminoethyl diphenylborinic acid, b-2-aminoethoxy diphenylborane, 2-diphenylboryl oxy ethanamine, borinic acid, o-2-aminoethyl diphenyl
1598
2-Aminoethyldiphenylborinat
NCCOB(C1=CC=CC=C1)C1=CC=CC=C1

Beschreibung

IP3 receptor antagonist. Also TRP channel modulator

A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42 μM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10 μM) and inhibits it at higher concentrations (up to 50 μM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes.
Chemischer Name oder Material 2-APB
Menge 10 mg
Formelmasse 225.1
Reinheit (%) >98%
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